Mr. Hillman:

I'm going to have Dr. Papadopoulos talk for about five minutes about his experience with AIDS patients at a hospital in Greece. And then we're going to have Dr. Tsilimigakis talk about his protocol with AIDS patients at his private office. So first, I'm going to have Dr. Antonios Papadopoulos talk.

Dr. Papadopoulos:

Thank you very much Mr. Hillman. I'd like to introduce ourselves. I'm Dr. Papadopoulos. I'm working in the First Hospital of Social Security, IKA in Athens, 4 Zaimi St., Melissia and our fax number is 301-804-2474. And we are working in an AIDS unit since 1987. We have seen, up to now, almost 320 patients with AIDS. We also run an endoscopy unit. Since 1987 we have been members in the European network of the project management groups for clinical research in the treatment of AIDS. We have also participated in various clinical protocols, . . . Euro AIDS, Euro SIDA and others.

We have had experience with the PAP-IMI device since February of this year. We have a permit from the Greek Drug Organization to run a protocol. First we have applied this device in patients with Kaposis sarcoma and other various painful lesions in order to ameliorate their symptoms. We apply this device twice per week for 25 minutes with power 4. We apply the probe over the spleen area, over the thymus area, the axillary area, in the neck area - over the neck lymph nodes, and in a few instances over painful lesions. We follow their CD4 and CD8 levels, their clinical progress, and some other laboratory parameters as well. . .

We have noticed no side effects or any other adverse effects from this application and we were very happy about this. We followed up all of these patients. In two of these patients with a rather high CD4 count, over 300 [Patients 11 and 12], we have applied this device, in order to see what's going on in this stage. All of these are in CDC stage A2.

So after we obtained a rather good profile in our first patients, we proceeded to carry out viral load measurements. Results are not yet available, but will be available very shortly, and we are anxiously waiting for these results. Because if the viral load measurements are compatible with the CD4 count increases, then we'll go on to treat other patients in less advanced stages of the HIV disease. That's what I'd like to quote briefly.

Mr. Dal Rio:

This is from Hospital Del Rio in Tijuana. Specifically in the Kaposi's sarcoma, Doctor, how do you suggest that the probe of the machine be located when the problem is spread all over the body?

Dr. Papadopoulos:

When the lesions of Kaposi's Sarcoma were extensive, of course we could not apply the probe all over the body. But when the lesions were rather limited, less than five, then we applied this probe over the area. And we noticed, at least in two patients, that we had a remarkable response. In one of them [Patient No. 1], after almost nine months application, we've seen no worsening and at least on one occasion a lessening of the size of the lesions. This patient who had a lessening of the lesions, he also has a very good condition and a very remarkable increase of CD4 count, from 266 to 558. And he has also gain weight, almost 5 kilograms during this period. In patients that had many lesions, we didn't see such an effect.

Teleconference Participants

U.S.

Dr. Charles Wallach, Ph.D., I.R.B. Chairman; Los Angeles, CA
Dr. P. L., Ph.D., Consultant; Schenectady, NY
Mr. Greg Hillman, Investor; Rector, PA
Mr. Chuck Wallach, C.E.O. PAP ElectroDynamics, U.S.A.; CA
Professor Saxena, Ph.D., Cornell School of Medicine; New York, NY

Mexico

Dr. Jeff Freeman, M.D., Clinic Owner; Tijuana, Mexico
Dr. Sergio Del Rio, M.D., Manner Clinic; Tijuana, Mexico
Dr. Savaedra, M.D., Clinic Owner; Tijuana, Mexico

Greece

Dr. Panos Pappas, Ph.D., PAP Electrodynamics, Athens, Greece
Dr. Papadopoulos, M.D., IKA Hospital, Athens, Greece
Dr. Ioannis Arkadianos, M.D., Clinic Owner; Athens, Greece
Dr. Nick Tsilimigakis, M.D., Clinic Owner; Athens, Greece
Dr. Zambackus, M.D., Clinic Owner, Athens, Greece

Switzerland

Mr. Rene Ruf, PAP IMI Distributor; Zug, Switzerland

Austria

Dr. Zimmerman, M.D., Clinic Owner, Austria